Automated oxygen control with O2matic^® during admission with exacerbation of COPD.

ABSTRACT:

Purpose

It is a challenge to control oxygen saturation (SpO₂) in patients with exacerbations of COPD during admission. We tested a newly developed closed-loop system, O2matic^®, and its ability to keep SpO₂ within a specified interval compared with manual control by nursing staff.

Patients and methods

We conducted a crossover trial with patients admitted with an exacerbation of COPD and hypoxemia (SpO₂ ≤88% on room air). Patients were monitored with continuous measurement of SpO₂. In random order, they had 4 hours with manually controlled oxygen and 4 hours with oxygen delivery controlled by O2matic. Primary outcome was time within a prespecified SpO₂ target interval. Secondary outcomes were time with SpO₂

SUBMITTER: Hansen EF 

PROVIDER: S-EPMC6300382 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature