Vitamin D Deficiency Is Associated With Poor Ovarian Stimulation Outcome in PCOS but Not Unexplained Infertility.

ABSTRACT:

Context

The impact of vitamin D deficiency on the success of ovarian stimulation according to underlying infertility diagnosis has not been investigated.

Objective

To evaluate the relationship between vitamin D deficiency and reproductive outcomes after ovarian stimulation in women with either polycystic ovary syndrome (PCOS) or unexplained infertility.

Design

Retrospective cohort study.

Setting

Analysis of randomized controlled trial (RCT) data.

Participants

Participants from the Pregnancy in Polycystic Ovary Syndrome II (PPCOS II) RCT (n = 607); participants from the Assessment of Multiple Intrauterine Gestations from Ovarian Stimulation (AMIGOS) RCT of unexplained infertility (n = 647).

Interventions

Serum 25(OH)D levels measured in banked sera

SUBMITTER: Butts SF 

PROVIDER: S-EPMC6300410 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature