Late-Onset T1DM and Older Age Predict Risk of Additional Autoimmune Disease.

ABSTRACT:

Objective

Type 1 diabetes (T1DM) is associated with other autoimmune diseases (AIDs), which may have serious health consequences. The epidemiology of AIDs in T1DM is not well defined in adults with T1DM. In this cross-sectional cohort study, we sought to characterize the incident ages and prevalence of AIDs in adults with T1DM across a wide age spectrum.

Research design and methods

A total of 1,212 adults seen at the Washington University Diabetes Center from 2011 to 2018 provided informed consent for the collection of their age, sex, race, and disease onset data. We performed paired association analyses based on age at onset of T1DM. Multivariate logistic regression was used to evaluate the independent effects of sex, race, T1DM age of onset, and T1DM duration on the preval

SUBMITTER: Hughes JW 

PROVIDER: S-EPMC6300704 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature