Abnormal orthostatic blood pressure control among subjects with lacunar infarction.

ABSTRACT:

Introduction

Hypertension is a recognised risk factor for lacunar stroke. However, their association has been evaluated using static blood pressure (BP) assessment in supine or sitting position alone. We hypothesised that impaired dynamic (orthostatic) BP control may associate with lacunar strokes.

Patients and methods

Consecutive subjects with mitral regurgitation (MR) confirmed, lacunar strokes were compared with two control groups. Firstly "normal", age and sex matched, population controls (1:3 ratio) and then 'at risk' controls matched for age, sex, hypertension history and antihypertensive medication (1:2 ratio). Orthostatic BP control was assessed by active stand tests with continuous, phasic, beat-to-beat BP measurement.

Findings

Thirty-six subjects (mean 69.9

SUBMITTER: Ryan DJ 

PROVIDER: S-EPMC6301241 | biostudies-literature | 2016 Sep

REPOSITORIES: biostudies-literature