Polymer-free versus durable polymer drug-eluting stents in patients with coronary artery disease: A meta-analysis.

ABSTRACT:

Background

Polymer-free drug-eluting stents (PF-DES) were introduced with the aim of reducing the risk of stent thrombosis associated with durable polymer drug-eluting stents (DP-DES). The comparison of safety and efficacy profiles between these two stent platforms remains unclear.

Materials and methods

We conducted electronic database searches for randomized controlled trials (RCTs) comparing patients treated with either PF-DES or DP-DES. Outcomes included definite or probable stent thrombosis (ST), myocardial infarction (MI), cardiac death, all-cause death, target lesion revascularization (TLR), and target vessel revascularization (TVR). A random-effects model was used to derive risk ratios (RRs) with 95% confidence intervals (CIs). Subgroup analyses based on different var

SUBMITTER: Wu JJ 

PROVIDER: S-EPMC6302254 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature