Effects of coronary revascularization on global coronary flow reserve in stable coronary artery disease.

ABSTRACT:

Aims

Coronary flow reserve (CFR) is an integrated measure of the entire coronary vasculature, and is a powerful prognostic marker in coronary artery disease (CAD). The extent to which coronary revascularization can improve CFR is unclear. This study aimed to evaluate the impact of percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG) on CFR in patients with stable CAD.

Methods and results

In a prospective, multicentre observational study, CFR was measured by 15O-water positron emission tomography as the ratio of stress to rest myocardial blood flow at baseline and 6 months after optimal medical therapy (OMT) alone, PCI, or CABG. Changes in the SYNTAX and Leaman scores were angiographically evaluated as indicators of completeness of revasculariza

SUBMITTER: Aikawa T 

PROVIDER: S-EPMC6302265 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature