Characterizing patient compliance over six months in remote digital trials of Parkinson's and Huntington disease.

ABSTRACT:

Background

A growing number of clinical trials use various sensors and smartphone applications to collect data outside of the clinic or hospital, raising the question to what extent patients comply with the unique requirements of remote study protocols. Compliance is particularly important in conditions where patients are motorically and cognitively impaired. Here, we sought to understand patient compliance in digital trials of two such pathologies, Parkinson's disease (PD) and Huntington disease (HD).

Methods

Patient compliance was assessed in two remote, six-month clinical trials of PD (n = 51, Clinician Input Study funded by the Michael J. Fox Foundation for Parkinson's Research) and HD (n = 17, sponsored by Teva Pharmaceuticals). We monitored four compliance metrics spec

SUBMITTER: Cohen S 

PROVIDER: S-EPMC6302308 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature