Bioactive Carbon-Based Hybrid 3D Scaffolds for Osteoblast Growth.

ABSTRACT: Bone, nerve, and heart tissue engineering place high demands on the conductivity of three-dimensional (3D) scaffolds. Fibrous carbon-based scaffolds are excellent material candidates to fulfill these requirements. Here, we show that highly porous (up to 94%) hybrid 3D framework structures with hierarchical architecture, consisting of microfiber composites of self-entangled carbon nanotubes (CNTs) and bioactive nanoparticles are highly suitable for growing cells. The hybrid 3D structures are fabricated by infiltrating a combination of CNTs and bioactive materials into a porous (∼94%) zinc oxide (ZnO) sacrificial template, followed by the removal of the ZnO backbone via a H₂ thermal reduction process. Simultaneously, the bioactive nanoparticles are sintered. In this way, conductiv

SUBMITTER: Taale M 

PROVIDER: S-EPMC6302313 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature