Maternal urinary 2-hydroxynaphthalene and birth outcomes in Taiyuan, China.

ABSTRACT:

Background

Naphthalene is the simplest polycyclic aromatic hydrocarbon (PAH). It is easily emitted into the atmosphere, posing a significant risk to human health. However, limited studies have described the impact of naphthalene exposure on birth outcomes. In this study, we investigated the association between the maternal urinary metabolites of naphthalene, 2-hydroxynaphthalene (2-OH NAP), and birth outcomes.

Method

In the present study, four urinary PAH metabolites were measured in 263 pregnant women during late pregnancy. Multiple linear regression analysis was used to analyze the relationship between the concentrations of 2-OH NAP and birth outcomes, and restricted cubic spline models were further used to examine the shapes of the dose-response association.

Result

SUBMITTER: Nie J 

PROVIDER: S-EPMC6302466 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature