Retinal Vasculometry Associations with Cardiometabolic Risk Factors in the European Prospective Investigation of Cancer-Norfolk Study.

ABSTRACT:

Purpose

To examine associations between retinal vessel morphometry and cardiometabolic risk factors in older British men and women.

Design

Retinal imaging examination as part of the European Prospective Investigation into Cancer-Norfolk Eye Study.

Participants

Retinal imaging and clinical assessments were carried out in 7411 participants. Retinal images were analyzed using a fully automated validated computerized system that provides novel measures of vessel morphometry.

Methods

Associations between cardiometabolic risk factors, chronic disease, and retinal markers were analyzed using multilevel linear regression, adjusted for age, gender, and within-person clustering, to provide percentage differences in tortuosity and absolute differences in width.

Main ou

SUBMITTER: Owen CG 

PROVIDER: S-EPMC6302796 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature