A databank for intracellular electrophysiological mapping of the adult somatosensory cortex.

ABSTRACT:

Background

Neurons in the supragranular layers of the somatosensory cortex integrate sensory (bottom-up) and cognitive/perceptual (top-down) information as they orchestrate communication across cortical columns. It has been inferred, based on intracellular recordings from juvenile animals, that supragranular neurons are electrically mature by the fourth postnatal week. However, the dynamics of the neuronal integration in adulthood is largely unknown. Electrophysiological characterization of the active properties of these neurons throughout adulthood will help to address the biophysical and computational principles of the neuronal integration.

Findings

Here, we provide a database of whole-cell intracellular recordings from 315 neurons located in the supragranular layers (L2/3

SUBMITTER: da Silva Lantyer A 

PROVIDER: S-EPMC6302958 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature