Predictors of first-year nonadherence and discontinuation of statins among older adults: a retrospective cohort study.

ABSTRACT:

Aims

The aim of this study was to examine the level of and predictors of statin nonadherence and discontinuation among older adults.

Methods

Among 22 340 Australians aged ≥65 years who initiated statin therapy from January 2014 to December 2015, we estimated the first-year nonadherence (proportion of days covered [PDC] <0.80) and discontinuation (≥90 days without statin coverage) rates. Predictors of nonadherence and discontinuation were examined via multivariable logistic regression. Analyses were performed separately for general beneficiaries (with a higher co-payment; n = 4841) and concessional beneficiaries (with a lower co-payment; n = 17 499).

Results

During the one-year follow-up, 55.1% were nonadherent (concessional 52.6%; general beneficiaries 64.2%) and 44.7

SUBMITTER: Ofori-Asenso R 

PROVIDER: S-EPMC6303220 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature