Predicting 7-year mortality for use with evidence-based guidelines for Prostate-Specific Antigen (PSA) testing: findings from a large prospective study of 123 697 Australian men.

ABSTRACT:

Objectives

To develop and validate a prediction model for short-term mortality in Australian men aged ≥45years, using age and self-reported health variables, for use when implementing the Australian Clinical Practice Guidelines for Prostate-Specific Antigen (PSA) Testing and Early Management of Test-Detected Prostate Cancer. Implementation of one of the Guideline recommendations requires an estimate of 7-year mortality.

Design

Prospective cohort study using questionnaire data linked to mortality data.

Setting

Men aged ≥45years randomly sampled from the general population of New South Wales, Australia, participating in the 45 and Up Study.

Participants

123 697 men who completed the baseline postal questionnaire (distributed from 1 January 2006 to 31 December 200

SUBMITTER: Joshy G 

PROVIDER: S-EPMC6303562 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature