Poststroke depression and risk of stroke recurrence and mortality: protocol of a meta-analysis and systematic review.

ABSTRACT: INTRODUCTION:A number of observational studies have indicated that poststroke depression could increase the risk of stroke outcomes. There is a meta-analysis indicating that poststroke depression is a risk factor of all-cause mortality. This paper reports the protocol for a systematic review and meta-analysis to clarify the associations of poststroke depression with stroke recurrence and mortality in order to determine whether poststroke depression is a predictor of stroke outcomes according to data extracted from relevant observational studies. METHODS AND ANALYSIS:MEDLINE, Web of Science databases, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews will be used to conduct the search. Published studies written in English will be included. The r

SUBMITTER: Cai W 

PROVIDER: S-EPMC6303620 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature