Risk factors for opioid-induced respiratory depression in surgical patients: a systematic review and meta-analyses.

ABSTRACT:

Objective

This systematic review and meta-analysis aim to evaluate the risk factors associated with postoperative opioid-induced respiratory depression (OIRD).

Design

Systematic review and meta-analysis.

Data sources

PubMed-MEDLINE, MEDLINE in-process, EMBASE, Cochrane Central Register of Controlled Trials, Cochrane Database of Systematic Reviews, PubMed and Clinicaltrials.gov (January 1946 to November 2017).

Eligibility criteria

The inclusion criteria were: (1) adult patients 18 years or older who were administered opioids after surgery and developed postoperative OIRD (OIRD group); (2) all studies which reported both OIRD events and associated risk factors; (3) all studies with reported data for each risk factor on patients with no OIRD (control group) and (4

SUBMITTER: Gupta K 

PROVIDER: S-EPMC6303633 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature