Role of diffusional kurtosis imaging in grading of brain gliomas: a protocol for systematic review and meta-analysis.

ABSTRACT: INTRODUCTION:Central nervous system (CNS) gliomas are the most common primary intra-axial brain tumours and pose variable treatment response according to their grade, therefore, precise staging is mandatory. Histopathological analysis of surgical tumour samples is still deemed as the state-of-the-art staging technique for gliomas due to the moderate specificity of the available non-invasive imaging modalities. A recently evolved analysis of the tissue water diffusion properties, known as diffusional kurtosis imaging (DKI), is a dimensionless metric, which quantifies water molecules' degree of non-Gaussian diffusion, hence reflects tissue microenvironment's complexity by means of non-invasive diffusion-weighted MRI acquisitions. The objective of this systematic review and meta-analysis is t

SUBMITTER: Abdalla G 

PROVIDER: S-EPMC6303635 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature