Stability and resilience of the intestinal microbiota in children in daycare - a 12 month cohort study.

ABSTRACT:

Background

We performed a 12-month cohort study of the stability and resilience of the intestinal microbiota of healthy children in daycare in Denmark in relation to diarrheal events and exposure to known risk factors for gastrointestinal health such as travelling and antibiotic use. In addition, we analyzed how gut microbiota recover from such exposures.

Results

We monitored 32 children in daycare aged 1-6 years. Fecal samples were submitted every second month during a one-year observational period. Information regarding exposures and diarrheal episodes was obtained through questionnaires. Bacterial communities were identified using 16S rRNA gene sequencing. The core microbiota (mean abundance > 95%) dominated the intestinal microbiota, and none of the tested exposures (dia

SUBMITTER: Mortensen MS 

PROVIDER: S-EPMC6303881 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature