Identification of vitamin D and other bone metabolism parameters as risk factors for primary bone marrow oedema syndrome.

ABSTRACT:

Background

The aetiology and pathogenesis of primary bone marrow oedema syndrome (BMES) remain unclear. This retrospective cross-sectional study in a large cohort of patients with BMES was performed to characterise the overall skeletal status and turnover in patients with BMES, with the aim of identifying risk factors for this disease.

Methods

Patients who were diagnosed with BMES on the basis of clinical and radiological (magnetic resonance imaging) findings in our outpatient clinic were identified retrospectively. Patient history, co-existing metabolic disorders, bone metabolism parameters (serum calcium, phosphate, 25-OH-D₃, bone-specific alkaline phosphatase, parathyroid hormone, and osteocalcin, and urinary deoxypyridinoline) and bone mineral density (as meas

SUBMITTER: Oehler N 

PROVIDER: S-EPMC6303903 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature