Global burden of Clostridium difficile infections: a systematic review and meta-analysis.

ABSTRACT:

Background

Clostridium difficile is a leading cause of morbidity and mortality in several countries. However, there are limited evidence characterizing its role as a global public health problem. We conducted a systematic review to provide a comprehensive overview of C. difficile infections (CDI) rates.

Methods

Seven databases were searched (January 2016) to identify studies and surveillance reports published between 2005 and 2015 reporting CDI incidence rates. CDI incidence rates for health care facility-associated (HCF), hospital onset-health care facility-associated, medical or general intensive care unit (ICU), internal medicine (IM), long-term care facility (LTCF), and community-associated (CA) were extracted and standardized. Meta-analysis was conducted u

SUBMITTER: Balsells E 

PROVIDER: S-EPMC6304170 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature