Coenzyme Q10 in acute influenza.

ABSTRACT:

Objectives

The goal of this investigation was to determine if acute influenza infection is associated with depletion of CoQ10 compared to healthy controls and to determine any associations between CoQ10 levels and illness severity and inflammatory biomarkers.

Patients and methods

We analyzed serum CoQ10 concentrations of patients with acute influenza enrolled in a randomized clinical trial prior to study drug administration. Patients were enrolled at a single urban tertiary care center over 3 influenza seasons (December 27, 2013 to March 31, 2016). Wilcoxon rank sum test was used to compare CoQ10 levels between influenza patients and healthy controls. Correlations with inflammatory biomarkers and severity of illness were assessed using Spearman correlation coefficient.

Re

SUBMITTER: Chase M 

PROVIDER: S-EPMC6304320 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature