Factors Associated with Indacaterol Response in Tuberculosis-Destroyed Lung with Airflow Limitation.

ABSTRACT: BACKGROUND:Pulmonary tuberculosis can result in anatomical sequelae, and cause airflow limitation. However, there are no treatment guidelines for patients with a tuberculosis-destroyed lung. Recently, indacaterol effectiveness in chronic obstructive pulmonary disease (COPD) patients with Tuberculosis history (INFINITY) study revealed indacaterol provided bronchodilation and symptom improvement in COPD patients with a tuberculosis-destroyed lung. METHODS:We conducted a post-hoc subgroup analysis of the randomized controlled trial, the INFINITY study, to determine factors associated with indacaterol response in a tuberculosis-destroyed lung with airflow limitation. Data from 68 patients treated with inhaled indacaterol, were extracted and analyzed. Factors associated with the response of for

SUBMITTER: Kim TH 

PROVIDER: S-EPMC6304328 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature