Prognostic factors of synchronous endometrial and ovarian endometrioid carcinoma.

ABSTRACT:

Objective

Gynecologists occasionally encounter synchronous endometrial and ovarian endometrioid carcinoma (SEO-EC) patients who show favorable prognosis than locally advanced or metastatic disease patients. This study aimed to elucidate prognostic factors of SEO-EC and identify patients who have a sufficiently low risk of recurrence without receiving adjuvant chemotherapy.

Methods

We retrospectively reviewed 46 patients with pathologically confirmed SEO-EC who underwent surgery at the National Cancer Center Hospital between 1997 and 2016. Immunohistochemical evaluation of DNA mismatch repair (MMR) protein expression were performed for both endometrial and ovarian tumors. Patient outcomes were analyzed according to clinicopathologic factors.

Results

From the multivaria

SUBMITTER: Yoneoka Y 

PROVIDER: S-EPMC6304406 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature