Association of pretreatment thrombocytosis with prognosis in ovarian cancer: a systematic review and meta-analysis.

ABSTRACT:

Objective

To investigate the association between pre-treatment thrombocytosis and prognosis in patients with ovarian cancer (OC).

Methods

PubMed, EMBASE, and the Cochrane Library were searched for articles regarding the prognosis of OC patients with pre-treatment thrombocytosis by the end of March 2018. Pooled estimates for overall survival (OS) and progression-free survival (PFS) events were calculated as hazard ratios (HRs) either on a fixed or random effect model by Stata 13.0 software. Funnel plot and Egger's test were applied to evaluate publication bias and sensitivity analyses were undertaken to estimate the strength of outcomes.

Results

Eleven studies that met the inclusion criteria were enrolled, including a total of 4,953 patients. Pooled results showed that

SUBMITTER: Ye Q 

PROVIDER: S-EPMC6304413 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature