Pure early zygotic genes in the Asian malaria mosquito Anopheles stephensi.

ABSTRACT:

Background

The Asian malaria mosquito, Anopheles stephensi, is a major urban malaria vector in the Middle East and on the Indian subcontinent. Early zygotic transcription, which marks the maternal-to-zygotic transition, has not been systematically studied in An. stephensi or any other Anopheles mosquitoes. Improved understanding of early embryonic gene expression in An. stephensi will facilitate genetic and evolutionary studies and help with the development of novel control strategies for this important disease vector.

Results

We obtained RNA-seq data in biological triplicates from four early An. stephensi embryonic time points. Using these data, we identified 70 and 153 pure early zygotic genes (pEZGs) under stringent and relaxed conditions, respectively. We show that these

SUBMITTER: Wu Y 

PROVIDER: S-EPMC6304767 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature