Genome divergence and increased virulence of outbreak associated Salmonella enterica subspecies enterica serovar Heidelberg.

ABSTRACT: Salmonella enterica serotype Heidelberg is primarily a poultry adapted serotype of Salmonella that can also colonize other hosts and cause human disease. In this study, we compared the genomes of outbreak associated non-outbreak causing Salmonella ser. Heidelberg strains from diverse hosts and geographical regions. Human outbreak associated strains in this study were from a 2015 multistate outbreak of Salmonella ser. Heidelberg involving 15 states in the United States which originated from bull calves. Our clinicopathologic examination revealed that cases involving Salmonella ser. Heidelberg strains were predominantly young, less than weeks-old, dairy calves. Pre-existing or concurrent disease was found in the majority of the calves.

SUBMITTER: Antony L 

PROVIDER: S-EPMC6304783 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature