Aspartate aminotransferase-to-platelet ratio index predicts prognosis of hepatocellular carcinoma after postoperative adjuvant transarterial chemoembolization.

ABSTRACT:

Background and aim

To investigate the value of the aspartate aminotransferase-to-platelet ratio index (APRI) and build a new nomogram for hepatocellular carcinoma (HCC) patients undergoing postoperative adjuvant transarterial chemoembolization (PATACE).

Methods

We retrospectively reviewed 351 patients with HCC undergoing PATACE. We collected baseline HCC patient characteristics to obtain the risk factors for determining poor disease-free survival (DFS) and early time to recurrence (TTR) after PATACE. The multivariate Cox proportional hazards model was used to build new nomogram based on significant prognostic factors of outcomes.

Results

We generated the cutoff value of the APRI as 0.50 using the X-tile to distinguish patients with different outcomes in the whole coho

SUBMITTER: Zhu GQ 

PROVIDER: S-EPMC6305141 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature