Molecular Patterns of Resistance Among Helicobacter pylori Strains in South-Western Poland.

ABSTRACT: Treatment failure of Helicobacter pylori infection is caused mainly by progressive antibiotic resistance among H. pylori strains. In Poland, the prevalence of H. pylori strains resistant to metronidazole is higher than in other developed countries, reaching almost 50%, and resistance to clarithromycin is as high as 30% and is still increasing, contributing to the failure of first-line therapy in approximately 70% of patients. Moreover, the introduction of levofloxacin to eradication therapy of H. pylori infection quickly led to the emergence of resistant strains. Therefore, a necessary approach in microbiological diagnostics of H. pylori infection should be determination of susceptibility of H. pylori strains before the eradication treatment. Ai

SUBMITTER: Binkowska A 

PROVIDER: S-EPMC6305312 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature