A Review of Oxygen Use During Chest Compressions in Newborns-A Meta-Analysis of Animal Data.

ABSTRACT: Background: International consensus statements for resuscitation of newborn infants recommend provision of 100% oxygen once chest compressions are required. However, 100% oxygen exacerbates reperfusion injury and reduces cerebral perfusion in newborn babies. Objective: We aimed to establish whether resuscitation with air during chest compression is feasible and safe in newborn infants compared with 100% oxygen. Methods: Systematic search of PubMed, Google Scholar and CINAHL for articles examining variable oxygen concentrations during chest compressions in term newborns. Results: Overall, no human studies but eight animal studies (n = 323 animals) comparing various oxygen concentrations during chest compression were identified. The pooled analysis showed n

SUBMITTER: Garcia-Hidalgo C 

PROVIDER: S-EPMC6305367 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature