Iris melanoma relapsing sixteen years after proton-beam therapy: The importance of lifelong follow-up.

ABSTRACT:

Purpose

To report a case of locally recurrent spindle-cell iris amelanotic melanoma 16 years after proton-beam therapy.

Observations

In 2001, a 45-year-old man presented with an amelanotic iris melanoma, extending from the 5 to 10 o'clock positions on his left eye. High-frequency ultrasonography showed extension of melanoma into the ciliary body. He was initially managed with proton-beam therapy (60 Gy delivered in four fractions over four consecutive days) and underwent ocular and systemic examination at regular intervals over the following years. Local tumor control was achieved, and the patient did not develop metastasis during sixteen consecutive years. In 2017, 16 years after he received proton-beam therapy, the patient developed a focal amelanotic lesion strongly sugge

SUBMITTER: Msika LC 

PROVIDER: S-EPMC6305799 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature