The efficacy of intravenous thrombolysis in acute ischemic stroke patients with white matter hyperintensity.

ABSTRACT:

Objectives

We aimed to investigate effects of deep white matter hyperintensity (DWMH) and periventricular hyperintensity (PVH) on the efficacy of intravenous thrombolysis (IVT) in patients with acute ischemic stroke (AIS).

Methods

A total of 113 AIS patients with WMH were categorized into the PVH group and the DWMH group according to the lesion location, with the division of two subgroups based on whether or not they received IVT treatment: the thrombolysis group and the control group. Kaplan-Meier analysis was used for proportional hazards of recurrent stroke. Further, multivariate Cox regression analysis was employed.

Results

Of total patients, there were 62 PVH patients and 51 DWMH patients: 27 of PVH patients and 22 of DWMH patients received IVT, and the remaining

SUBMITTER: Liu Y 

PROVIDER: S-EPMC6305931 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature