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Association between bisphenol A diglycidyl ether-specific IgG in serum and food sensitization in young children.


ABSTRACT:

Background

Recent studies have reported that endocrine-disrupting compound (EDC) exposure is related to food sensitization. Bisphenol A diglycidyl ether (BADGE) is one of the most widespread EDCs and its biological effects are considered to be greater on children than on adults. This study investigated the relationship between serum BADGE-specific immunoglobulin G (IgG) concentrations and food sensitization in young children by measuring food-specific IgE levels.

Methods

In total, 98 young children (59 boys and 39 girls; median age: 7 months; 25th and 75th percentile ages: 6 and 8 months, respectively) were enrolled. Blood samples were collected twice from all children (median sampling interval: 6 months; 25th and 75th percentile: 5 and 7 months). Food sensitization was eval

SUBMITTER: Tsuji M 

PROVIDER: S-EPMC6306001 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature