Association Between Preceding Viral Respiratory Infection and Subsequent Respiratory Illnesses Among Children: A Prospective Cohort Study in the Philippines.

ABSTRACT:

Background

Acute respiratory infection (ARI) is of great concern in public health. It remains unclear whether viral infections can affect the host's susceptibility to subsequent ARIs.

Methods

A prospective cohort study on ARIs of children below 5 years old was conducted in the Philippines from 2014 to 2016. The respiratory symptoms were recorded daily, and nasopharyngeal swabs were collected at both household and health facilities. The specimens were tested for respiratory viruses. We then determined whether viral etiology was associated with the severity of the present ARI and whether previous viral infections was associated with subsequent ARIs.

Results

A total of 3851 children and 16337 ARI episodes were enrolled and recorded, respectively. Samples were collected f

SUBMITTER: Furuse Y 

PROVIDER: S-EPMC6306022 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature