Functional MRI connectivity of children with autism and low verbal and cognitive performance.

ABSTRACT:

Background

Functional neuroimaging research in autism spectrum disorder has reported patterns of decreased long-range, within-network, and interhemispheric connectivity. Research has also reported increased corticostriatal connectivity and between-network connectivity for default and attentional networks. Past studies have excluded individuals with autism and low verbal and cognitive performance (LVCP), so connectivity in individuals more significantly affected with autism has not yet been studied. This represents a critical gap in our understanding of brain function across the autism spectrum.

Methods

Using behavioral support procedures adapted from Nordahl, et al. (J Neurodev Disord 8:20-20, 2016), we completed non-sedated structural and functional MRI scans of 56 children

SUBMITTER: Gabrielsen TP 

PROVIDER: S-EPMC6307191 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature