Cell Type Specific Representation of Vibro-tactile Stimuli in the Mouse Primary Somatosensory Cortex.

ABSTRACT: Although the processing of whisker deflections in the barrel area of the rodent primary somatosensory cortex (S1) has been studied extensively, how cutaneous vibro-tactile stimuli are processed in the rodent S1 outside the barrel area has not been fully examined. Particularly, the cell-type specific representation of multiple vibration frequencies in genetically identified inhibitory cells in the S1 has not been examined. Using two-photon calcium imaging, we examined the responses to vibration stimuli of excitatory and inhibitory neurons in the S1 hind limb area of male and female mice. The excitatory cells showed relatively sharp selectivity to vibration stimuli, whereas the inhibitory cells exhibited less selectivity. The excitatory and inhibitory cells with different preferred stimuli w

SUBMITTER: Hayashi A 

PROVIDER: S-EPMC6307530 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature