Prevalence and prognostic implication of iron deficiency and anaemia in patients with severe aortic stenosis.

ABSTRACT:

Objective

The aim of this study was to evaluate the prevalence and prognostic implication of iron deficiency (ID) and anaemia in patients with severe aortic stenosis (AS).

Methods

In an observational study of consecutive patients referred for aortic valve replacement (AVR), we assessed a wide range of biomarkers of iron status, including the definition of ID commonly applied in patients with chronic heart failure (ferritin <100 µg/L or ferritin 100-299 µg/L with a transferrin saturation <20%). The endpoints were short-term (one-year) and long-term (median 4.7 years, IQR: 3.8-5.5) mortality and major adverse cardiovascular events (MACE) within the first year after inclusion.

Results

464 patients were included in this substudy. 91 patients (20%) received conservative tr

SUBMITTER: Kvaslerud AB 

PROVIDER: S-EPMC6307621 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature