Behavior Responses to Chemical and Optogenetic Stimuli in Drosophila Larvae.

ABSTRACT: An animal's ability to navigate an olfactory environment is critically dependent on the activities of its first-order olfactory receptor neurons (ORNs). While considerable research has focused on ORN responses to odorants, the mechanisms by which olfactory information is encoded in the activities of ORNs and translated into navigational behavior remain poorly understood. We sought to determine the contributions of most Drosophila melanogaster larval ORNs to navigational behavior. Using odorants to activate ORNs and a larval tracking assay to measure the corresponding behavioral response, we observed that larval ORN activators cluster into four groups based on the behavior responses elicited from larvae. This is significant because it provides new insights into the functional relatio

SUBMITTER: Clark DA 

PROVIDER: S-EPMC6308144 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature