Quantifying Differences Between Passive and Task-Evoked Intrinsic Functional Connectivity in a Large-Scale Brain Simulation.

ABSTRACT: Establishing a connection between intrinsic and task-evoked brain activities is critical because it would provide a way to map task-related brain regions in patients unable to comply with such tasks. A crucial question within this realm is to what extent the execution of a cognitive task affects the intrinsic activity of brain regions not involved in the task. Computational models can be useful to answer this question because they allow us to distinguish task from nontask neural elements while giving us the effects of task execution on nontask regions of interest at the neuroimaging level. The quantification of those effects in a computational model would represent a step toward elucidating the intrinsic versus task-evoked connection. In this study we used computational modeling and graph

SUBMITTER: Ulloa A 

PROVIDER: S-EPMC6308294 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature