EINVis: a visualization tool for analyzing and exploring genetic interactions in large-scale association studies.

ABSTRACT: Epistasis (gene-gene interaction) detection in large-scale genetic association studies has recently drawn extensive research interests as many complex traits are likely caused by the joint effect of multiple genetic factors. The large number of possible interactions poses both statistical and computational challenges. A variety of approaches have been developed to address the analytical challenges in epistatic interaction detection. These methods usually output the identified genetic interactions and store them in flat file formats. It is highly desirable to develop an effective visualization tool to further investigate the detected interactions and unravel hidden interaction patterns. We have developed EINVis, a novel visualization tool that is specifically designed to analyze and explore

SUBMITTER: Wu Y 

PROVIDER: S-EPMC6309325 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature