Age-related changes in neural mechanisms of prospective memory.

ABSTRACT: The capability to remember and execute intentions in the future - termed prospective memory (PM) - may be of special significance for older adults to enable successful completion of important activities of daily living. Despite the importance of this cognitive function, mixed findings have been obtained regarding age-related decline in PM, and, currently, there is limited understanding of potential contributing mechanisms. In the current study, older (N=41) and younger adults (N=47) underwent task-functional MRI during performance of PM conditions that encouraged either spontaneous retrieval (Focal) or sustained attentional monitoring (Non-focal) to detect PM targets. Older adults exhibited a reduction in PM-related sustained activity within the anterior prefrontal cortex (aPFC) and associ

SUBMITTER: Lamichhane B 

PROVIDER: S-EPMC6309350 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature