Efficacy of Misoprostol Alone for First-Trimester Medical Abortion: A Systematic Review.

ABSTRACT:

Objective

To summarize available data on the effectiveness and safety of single-agent misoprostol for medical abortion in the first trimester.

Data sources

We searched MEDLINE, CABI, Cochrane, EMBASE, LILACS, the Web of Science, and ClinicalTrials.gov for English-language studies that evaluated misoprostol alone for abortion of a viable pregnancy in the first trimester.

Methods of study selection

Our search yielded 1,562 citations, of which 38 included data from 53 trial groups that met our inclusion and exclusion criteria.

Tabulation, integration, and results

We abstracted data about each trial group, including study characteristics, treatment regimen, clinical protocol, number of women treated and followed, and numbers with outcomes of interest. We used meta-

SUBMITTER: Raymond EG 

PROVIDER: S-EPMC6309472 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature