Albuminuria and Allograft Failure, Cardiovascular Disease Events, and All-Cause Death in Stable Kidney Transplant Recipients: A Cohort Analysis of the FAVORIT Trial.

ABSTRACT:

Rationale & objective

Cardiovascular disease (CVD) is common and overall graft survival is suboptimal among kidney transplant recipients. Although albuminuria is a known risk factor for adverse outcomes among persons with native chronic kidney disease, the relationship of albuminuria with cardiovascular and kidney outcomes in transplant recipients is uncertain.

Study design

Post hoc longitudinal cohort analysis of the Folic Acid for Vascular Outcomes Reduction in Transplantation (FAVORIT) Trial.

Setting & participants

Stable kidney transplant recipients with elevated homocysteine levels from 30 sites in the United States, Canada, and Brazil.

Predictor

Urine albumin-creatinine ratio (ACR) at randomization.

Outcomes

Allograft failure, CVD, and all-cause de

SUBMITTER: Weiner DE 

PROVIDER: S-EPMC6309643 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature