Breastfeeding duration modifies the effect of smoking during pregnancy on eczema from early childhood to adolescence.

ABSTRACT:

Background

Cigarette smoke contains compounds similar to coal tar, an ancient remedy of eczema. Some studies have reported protective effects of maternal gestational smoking on offspring eczema; however, others have shown no or increased risks. Similarly, studies linking breastfeeding duration and eczema have demonstrated contradictory findings. No study has yet investigated combined effects of these two factors on eczema.

Objective

Since tobacco compounds can pass to offspring via breast milk, we investigated their combined effects on eczema development from childhood to adolescence.

Methods

We obtained information regarding gestational smoking, exclusive breastfeeding duration, and eczema at ages 1-or-2, 4, 10, and 18 years from the Isle of Wight (IOW) birth cohort,

SUBMITTER: Mukherjee N 

PROVIDER: S-EPMC6309780 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature