Weight Gain Trajectory Predicts Long-term Overweight and Obesity After Pediatric Liver Transplant.

ABSTRACT:

Objective

The aim of the study is to identify early predictors of long-term overweight and obesity in pediatric liver transplant recipients.

Methods

Single-center, retrospective review of children who underwent liver transplant before age 6 years. Body mass index (BMI), weight, and height percentiles at transplant and post-transplant were calculated. BMI, weight gain trajectories, and failure-to-thrive (FTT) were examined as predictors of overweight/obesity at 3 and 5 years post-transplant.

Results

Children (n = 70) were median 0.9 years at transplant. Median BMI percentile increased from 37 (interquartile range (IQR) 12-73) at transplant to 83 (IQR 64-97) at 12 months, with median weight percentile 47 (IQR 26-67) and height percentile 9 (IQR 2-32). Overweight/obesity

SUBMITTER: Swenson SM 

PROVIDER: S-EPMC6310111 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature