Arterial involvement in Erdheim-Chester disease: A retrospective cohort study.

ABSTRACT: Erdheim-Chester disease (ECD) is a rare histiocytosis of the "L" (Langerhans) group with multisystem involvement that can affect the large and medium-sized arteries mimicking vasculitis. Aortic involvement is common but the frequency and outcome of aortic branch vessel abnormalities are less well described.Patients with ECD were retrospectively identified. Images containing information of arterial involvement within 6 months of diagnosis were considered baseline and compared to last follow-up studies. Two physicians independently reviewed the studies to evaluate for presence of abnormalities attributable to ECD. Age and sex-adjusted logistic regression models were used to examine associations between patient characteristics and vessel involvement at baseline.Among a cohort of 64 patients w

SUBMITTER: Villatoro-Villar M 

PROVIDER: S-EPMC6310516 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature