Association between Helicobacter pylori infection and Sjogren syndrome: A meta-analysis.

ABSTRACT:

Background

Helicobacter pylori has been proved as a risk factor of many diseases. There are some researches trying to find connection between H. pylori and Sjögren syndrome (SS). However, the conclusions of these studies are controversial. We conducted this meta-analysis to evaluate the association between H. pylori and SS.

Methods

We searched PubMed and Embase databases for researches which include the data of H. pylori infection rate in SS and control groups. A fixed-effects model was used to analyze the risk odds ratio (OR) with 95% confidence intervals (CIs) according to the heterogeneity across the selected studies.

Results

Nine studies with 1958 participants including 619 patients with SS met the inclusion criteria. The total infection rate of H. pylori was 53.8

SUBMITTER: Chen Q 

PROVIDER: S-EPMC6310521 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature