The effect of respiration-driven flow waveforms on hemodynamic metrics used in Fontan surgical planning.

ABSTRACT:

Objective

Poor total cavopulmonary connection (TCPC) hemodynamics have been hypothesized to be associated with long-term complications in Fontan patients. Image-based Fontan surgical planning has shown great potential as a clinical tool because it can pre-operatively evaluate patient-specific hemodynamics. Current surgical planning paradigms commonly utilize cardiac-gated phase contrast magnetic resonance (MR) imaging to acquire vessel flows. These acquisitions are often taken under breath-held (BH) conditions and ignore the effect of respiration on blood flow waveforms. This study investigates the effect of respiration-driven flow waveforms on patient-specific hemodynamics using real-time MR acquisitions.

Methods

Patient-specific TCPCs were reconstructed from cardiovascular

SUBMITTER: Tang E 

PROVIDER: S-EPMC6310625 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature