Non-atopic rhinitis at age 6 is associated with subsequent development of asthma.

ABSTRACT:

Background

It has been postulated that the association between allergic rhinitis and asthma is attributable to the progressive clinical expression of respiratory inflammation during childhood. The role of non-allergic rhinitis in early life in relation to subsequent asthma has not been extensively explored.

Objective

We sought to determine whether rhinitis in early life was associated with risk of asthma development into adulthood, and whether this relationship is independent of allergic sensitization.

Methods

Participants were identified from the Tucson Children's Respiratory Study, a non-selected birth cohort. Allergy skin prick testing was performed at age 6 years using house dust mix, Bermuda, mesquite, olive, mulberry, careless weed, and Alternaria aeroallergens.

SUBMITTER: Carr TF 

PROVIDER: S-EPMC6310646 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature