Measurement of glomerular filtration rate in patients undergoing obesity surgery.

ABSTRACT:

Background

Most studies on obesity surgery have measured renal function using the estimated GFR. However, due to the reduction of muscle mass, and therefore creatinine that accompanies weight loss, such measures can falsely suggest an improvement in renal function. To balance the risks of surgery versus any potential benefits on renal function, we need to be able to determine renal function using valid and reliable methodologies. In this pilot study we aimed to measure renal function in patients with CKD undergoing obesity surgery using the gold standard ⁵¹Cr-EDTA GFR clearance methodology which is independent of measures of muscle mass.

Methods

Nine consecutive obese patients with CKD underwent obesity surgery. Their renal function was assessed using ⁵¹

SUBMITTER: Chuah LL 

PROVIDER: S-EPMC6311002 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature