Long-term exposure of Aedes aegypti to Bacillus thuringiensis svar. israelensis did not involve altered susceptibility to this microbial larvicide or to other control agents.

ABSTRACT:

Background

Bacillus thuringiensis svar. israelensis (Bti) is an effective and safe biolarvicide to control Aedes aegypti. Its mode of action based on four protoxins disfavors resistance; however, control in endemic areas that display high mosquito infestation throughout the year requires continuous larvicide applications, which imposes a strong selection pressure. Therefore, this study aimed to investigate the effects of an intensive Bti exposure on an Ae. aegypti strain (RecBti), regarding its susceptibility to Bti and two of its protoxins tested individually, to other control agents temephos and diflubenzuron, and its profile of detoxifying enzymes.

Methods

The RecBti strain was established using a large egg sample (10,000) from Recife city (Brazil) and more than 290,000 l

SUBMITTER: Carvalho KDS 

PROVIDER: S-EPMC6311009 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature