Asymptomatic Plasmodium vivax infections among Duffy-negative population in Kedougou, Senegal.

ABSTRACT:

Background

In the southeastern Senegal, the report of Plasmodium vivax infections among febrile patients in Kedougou constitutes a new emerging health problem.

Methods

Samples from 48 asymptomatic schoolchildren sampled twice a year over 2 years were used to explore the reservoir of P. vivax parasite infections in this region. Both Duffy genotyping and Plasmodium species diagnostic assays were performed.

Results

PCR assays detected Plasmodium genomic DNA in 38.5% (74/192) of samples. Pure P. falciparum and P. vivax infections were identified in 79.7% (59/74) and 20.3% (15/74) of samples, respectively. All schoolchildren were classified as Duffy-negative by genotyping. P. vivax infections were detected in five children:

SUBMITTER: Niang M 

PROVIDER: S-EPMC6311047 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature